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A Cell-Based Strategy To Assess Intrinsic Inhibition Efficiencies of HIV-1 Reverse Transcriptase Inhibitors
During HIV-1 reverse transcription, there are increasing opportunities for nucleos(t)ide (NRTI) or nonnucleoside (NNRTI) reverse transcriptase (RT) inhibitors to stop elongation of the nascent viral DNA (vDNA). In addition, RT inhibitors appear to influence the kinetics of vDNA synthesis differently...
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Publicat a: | Antimicrob Agents Chemother |
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Autors principals: | , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
American Society for Microbiology
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335843/ https://ncbi.nlm.nih.gov/pubmed/25403670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04163-14 |
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