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Drug Susceptibility and Viral Fitness of HIV-1 with Integrase Strand Transfer Inhibitor Resistance Substitution Q148R or N155H in Combination with Nucleoside/Nucleotide Reverse Transcriptase Inhibitor Resistance Substitutions

In clinical trials of coformulated elvitegravir (EVG), cobicistat (COBI), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF), emergent drug resistance predominantly involved the FTC resistance substitution M184V/I in reverse transcriptase (RT), with or without the tenofovir (TFV) resistanc...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Andreatta, Kristen N., Miller, Michael D., White, Kirsten L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750659/
https://ncbi.nlm.nih.gov/pubmed/26574015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02096-15
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