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HIV-1 and HIV-2 Reverse Transcriptases: Different Mechanisms of Resistance to Nucleoside Reverse Transcriptase Inhibitors

As anti-HIV therapy becomes more widely available in developing nations, it is clear that drug resistance will continue to be a major problem. The related viruses HIV-1 and HIV-2 share many of the same resistance pathways to nucleoside reverse transcriptase inhibitors (NRTIs). However, clinical data...

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Hlavní autoři: Boyer, Paul L., Clark, Patrick K., Hughes, Stephen H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347278/
https://ncbi.nlm.nih.gov/pubmed/22438533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06597-11
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