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Altered Viral Fitness and Drug Susceptibility in HIV-1 Carrying Mutations That Confer Resistance to Nonnucleoside Reverse Transcriptase and Integrase Strand Transfer Inhibitors

Nonnucleoside reverse transcriptase (RT) inhibitors (NNRTI) and integrase (IN) strand transfer inhibitors (INSTI) are key components of antiretroviral regimens. To explore potential interactions between NNRTI and INSTI resistance mutations, we investigated the combined effects of these mutations on...

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Bibliografiske detaljer
Main Authors: Hu, Zixin, Kuritzkes, Daniel R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136249/
https://ncbi.nlm.nih.gov/pubmed/24899199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00695-14
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