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Altered Viral Fitness and Drug Susceptibility in HIV-1 Carrying Mutations That Confer Resistance to Nonnucleoside Reverse Transcriptase and Integrase Strand Transfer Inhibitors

Nonnucleoside reverse transcriptase (RT) inhibitors (NNRTI) and integrase (IN) strand transfer inhibitors (INSTI) are key components of antiretroviral regimens. To explore potential interactions between NNRTI and INSTI resistance mutations, we investigated the combined effects of these mutations on...

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Bibliographische Detailangaben
Hauptverfasser: Hu, Zixin, Kuritzkes, Daniel R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136249/
https://ncbi.nlm.nih.gov/pubmed/24899199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00695-14
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