Preclinical Evaluation of GS-9160, a Novel Inhibitor of Human Immunodeficiency Virus Type 1 Integrase

GS-9160 is a novel and potent inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase (IN) that specifically targets the process of strand transfer. It is an authentic inhibitor of HIV-1 integration, since treatment of infected cells results in an elevation of two-long terminal repeat cir...

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Main Authors: Jones, Gregg S., Yu, Fang, Zeynalzadegan, Ameneh, Hesselgesser, Joseph, Chen, Xiaowu, Chen, James, Jin, Haolun, Kim, Choung U., Wright, Matthew, Geleziunas, Romas, Tsiang, Manuel
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2009
Ábhair:
Antiviral Agents
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650545/
https://ncbi.nlm.nih.gov/pubmed/19104010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00984-08
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