Search for small molecule activators of latent HIV

por Geleziunas, Romas, Stepan, George, Wei, George, Yu, Helen, Graupe, Michael, Pagratis, Nikos, Barnes, Tiffany, Cihlar, Tomas, Hesselgesser, Joe
Publicado 2012

Novel Hepatitis C Virus Reporter Replicon Cell Lines Enable Efficient Antiviral Screening against Genotype 1a

por Robinson, Margaret, Yang, Huiling, Sun, Siu-Chi, Peng, Betty, Tian, Yang, Pagratis, Nikos, Greenstein, Andrew E., Delaney, William E.
Publicado 2010

Optimized high-throughput screen for Hepatitis C virus translation inhibitors

por Berry, Katherine E., Peng, Betty, Koditek, David, Beeman, Douglas, Pagratis, Nikos, Perry, Jason K., Parrish, Jay, Zhong, Weidong, Doudna, Jennifer A., Shih, I-hung
Publicado 2011

Affinities between the Binding Partners of the HIV-1 Integrase Dimer-Lens Epithelium-derived Growth Factor (IN Dimer-LEDGF) Complex

por Tsiang, Manuel, Jones, Gregg S., Hung, Magdeleine, Mukund, Susmith, Han, Bin, Liu, Xiaohong, Babaoglu, Kerim, Lansdon, Eric, Chen, Xiaowu, Todd, Jacob, Cai, Terrence, Pagratis, Nikos, Sakowicz, Roman, Geleziunas, Romas
Publicado 2009

Homogeneous BTK Occupancy Assay for Pharmacodynamic Assessment of Tirabrutinib (GS-4059/ONO-4059) Target Engagement

por Yu, Helen, Truong, Hoa, Mitchell, Scott A., Liclican, Albert, Gosink, John J., Li, Wanying, Lin, Julie, Feng, Joy Y., Jürgensmeier, Juliane M., Billin, Andrew, Xu, Ren, Patterson, Scott, Pagratis, Nikos
Publicado en SLAS Discov (2018)

Study of Marine Natural Products Including Resorcyclic Acid Lactones from Humicola fuscoatra That Reactivate Latent HIV-1 Expression in an in Vitro Model of Central Memory CD4+ T C...

por Mejia, Eric J., Loveridge, Steven T., Stepan, George, Tsai, Angela, Jones, Gregg S., Barnes, Tiffany, White, Kimberly N., Drašković, Marija, Tenney, Karen, Tsiang, Manuel, Geleziunas, Romas, Cihlar, Tomas, Pagratis, Nikos, Tian, Yang, Yu, Helen, Crews, Phillip
Publicado 2014

Abyssomicin 2 Reactivates Latent HIV-1 by a PKC- and HDAC-Independent Mechanism

por León, Brian, Navarro, Gabriel, Dickey, Bailey J., Stepan, George, Tsai, Angela, Jones, Gregg S., Morales, Monica E., Barnes, Tiffany, Ahmadyar, Shekeba, Tsiang, Manuel, Geleziunas, Romas, Cihlar, Tomas, Pagratis, Nikos, Tian, Yang, Yu, Helen, Linington, Roger G.
Publicado en Org Lett (2015)

In Vitro Antiviral Activity and Resistance Profile Characterization of the Hepatitis C Virus NS5A Inhibitor Ledipasvir

por Cheng, Guofeng, Tian, Yang, Doehle, Brian, Peng, Betty, Corsa, Amoreena, Lee, Yu-Jen, Gong, Ruoyu, Yu, Mei, Han, Bin, Xu, Simin, Dvory-Sobol, Hadas, Perron, Michel, Xu, Yili, Mo, Hongmei, Pagratis, Nikos, Link, John O., Delaney, William
Publicado en Antimicrob Agents Chemother (2016)

A Small-Molecule Inhibitor of Hepatitis C Virus Infectivity

por Bush, Caroline O., Pokrovskii, Maria V., Saito, Roland, Morganelli, Philip, Canales, Eda, Clarke, Michael O., Lazerwith, Scott E., Golde, Justin, Reid, Brian G., Babaoglu, Kerim, Pagratis, Nikos, Zhong, Weidong, Delaney, William E., Paulson, Matthew S., Beran, Rudolf K. F.
Publicado 2014

Clinical targeting of HIV capsid protein with a long-acting small molecule

por Link, John O., Rhee, Martin S., Tse, Winston C., Zheng, Jim, Somoza, John R., Rowe, William, Begley, Rebecca, Chiu, Anna, Mulato, Andrew, Hansen, Derek, Singer, Eric, Tsai, Luong K., Bam, Rujuta A., Chou, Chien-Hung, Canales, Eda, Brizgys, Gediminas, Zhang, Jennifer R., Li, Jiayao, Graupe, Michael, Morganelli, Philip, Liu, Qi, Wu, Qiaoyin, Halcomb, Randall L., Saito, Roland D., Schroeder, Scott D., Lazerwith, Scott E., Bondy, Steven, Jin, Debi, Hung, Magdeleine, Novikov, Nikolai, Liu, Xiaohong, Villaseñor, Armando G., Cannizzaro, Carina E., Hu, Eric Y., Anderson, Robert L., Appleby, Todd C., Lu, Bing, Mwangi, Judy, Liclican, Albert, Niedziela-Majka, Anita, Papalia, Giuseppe A., Wong, Melanie H., Leavitt, Stephanie A., Xu, Yili, Koditek, David, Stepan, George J., Yu, Helen, Pagratis, Nikos, Clancy, Sheila, Ahmadyar, Shekeba, Cai, Terrence Z., Sellers, Scott, Wolckenhauer, Scott A., Ling, John, Callebaut, Christian, Margot, Nicolas, Ram, Renee R., Liu, Ya-Pei, Hyland, Rob, Sinclair, Gary I., Ruane, Peter J., Crofoot, Gordon E., McDonald, Cheryl K., Brainard, Diana M., Lad, Latesh, Swaminathan, Swami, Sundquist, Wesley I., Sakowicz, Roman, Chester, Anne E., Lee, William E., Daar, Eric S., Yant, Stephen R., Cihlar, Tomas
Publicado en Nature (2020)