Two new monoclonal antibodies for biochemical and flow cytometric analyses of human interferon regulatory factor-3 activation, turnover, and depletion

Por Rustagi, Arjun, Doehle, Brian P., McElrath, M. Juliana, Gale, Michael
Publicado em 2012

A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor

Por Bogerd, Hal P., Doehle, Brian P., Wiegand, Heather L., Cullen, Bryan R.
Publicado em 2004

A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins

Por Wiegand, Heather L, Doehle, Brian P, Bogerd, Hal P, Cullen, Bryan R
Publicado em 2004

The Intrinsic Antiretroviral Factor APOBEC3B Contains Two Enzymatically Active Cytidine Deaminase Domains

Por Bogerd, Hal P., Wiegand, Heather L., Doehle, Brian P., Cullen, Bryan R.
Publicado em 2007

Overexpression of Exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs

Por YI, RUI, DOEHLE, BRIAN P., QIN, YI, MACARA, IAN G., CULLEN, BRYAN R.
Publicado em 2005

Differential Sensitivity of Murine Leukemia Virus to APOBEC3-Mediated Inhibition Is Governed by Virion Exclusion

Por Doehle, Brian P., Schäfer, Alexandra, Wiegand, Heather L., Bogerd, Hal P., Cullen, Bryan R.
Publicado em 2005

APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells

Por Bogerd, Hal P., Wiegand, Heather L., Doehle, Brian P., Lueders, Kira K., Cullen, Bryan R.
Publicado em 2006

Human Immunodeficiency Virus Type 1 Mediates Global Disruption of Innate Antiviral Signaling and Immune Defenses within Infected Cells

Por Doehle, Brian P., Hladik, Florian, McNevin, John P., McElrath, M. Juliana, Gale, Michael
Publicado em 2009

Vpu Mediates Depletion of Interferon Regulatory Factor 3 during HIV Infection by a Lysosome-Dependent Mechanism

Por Doehle, Brian P., Chang, Kristina, Rustagi, Arjun, McNevin, John, McElrath, M. Juliana, Gale, Michael
Publicado em 2012

A Complex Network of Interactions between S282 and G283 of Hepatitis C Virus Nonstructural Protein 5B and the Template Strand Affects Susceptibility to Sofosbuvir and Ribavirin

Por Kulkarni, Anupriya S., Damha, Masad J., Schinazi, Raymond F., Mo, Hongmei, Doehle, Brian, Sagan, Selena M., Götte, Matthias
Publicado no Antimicrob Agents Chemother (2016)

Vpu-Deficient HIV Strains Stimulate Innate Immune Signaling Responses in Target Cells

Por Doehle, Brian P., Chang, Kristina, Fleming, Lamar, McNevin, John, Hladik, Florian, McElrath, M. Juliana, Gale, Michael
Publicado em 2012

The Betaretrovirus Mason-Pfizer Monkey Virus Selectively Excludes Simian APOBEC3G from Virion Particles

Por Doehle, Brian P., Bogerd, Hal P., Wiegand, Heather L., Jouvenet, Nolwenn, Bieniasz, Paul D., Hunter, Eric, Cullen, Bryan R.
Publicado em 2006

Clinical Resistance to Velpatasvir (GS-5816), a Novel Pan-Genotypic Inhibitor of the Hepatitis C Virus NS5A Protein

Por Lawitz, Eric J., Dvory-Sobol, Hadas, Doehle, Brian P., Worth, Angela S., McNally, John, Brainard, Diana M., Link, John O., Miller, Michael D., Mo, Hongmei
Publicado no Antimicrob Agents Chemother (2016)

IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

Por Negash, Amina A., Ramos, Hilario J., Crochet, Nanette, Lau, Daryl T. Y., Doehle, Brian, Papic, Neven, Delker, Don A., Jo, Juandy, Bertoletti, Antonio, Hagedorn, Curt H., Gale, Michael
Publicado em 2013

In Vitro Antiviral Activity and Resistance Profile Characterization of the Hepatitis C Virus NS5A Inhibitor Ledipasvir

Por Cheng, Guofeng, Tian, Yang, Doehle, Brian, Peng, Betty, Corsa, Amoreena, Lee, Yu-Jen, Gong, Ruoyu, Yu, Mei, Han, Bin, Xu, Simin, Dvory-Sobol, Hadas, Perron, Michel, Xu, Yili, Mo, Hongmei, Pagratis, Nikos, Link, John O., Delaney, William
Publicado no Antimicrob Agents Chemother (2016)