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Vpu Mediates Depletion of Interferon Regulatory Factor 3 during HIV Infection by a Lysosome-Dependent Mechanism

HIV has evolved sophisticated mechanisms to avoid restriction by intracellular innate immune defenses that otherwise serve to control acute viral infection and virus dissemination. Innate defenses are triggered when pattern recognition receptor (PRR) proteins of the host cell engage pathogen-associa...

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Bibliografske podrobnosti
Main Authors: Doehle, Brian P., Chang, Kristina, Rustagi, Arjun, McNevin, John, McElrath, M. Juliana, Gale, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421752/
https://ncbi.nlm.nih.gov/pubmed/22593165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00423-12
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