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Vpu Mediates Depletion of Interferon Regulatory Factor 3 during HIV Infection by a Lysosome-Dependent Mechanism

HIV has evolved sophisticated mechanisms to avoid restriction by intracellular innate immune defenses that otherwise serve to control acute viral infection and virus dissemination. Innate defenses are triggered when pattern recognition receptor (PRR) proteins of the host cell engage pathogen-associa...

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Bibliografische gegevens
Hoofdauteurs: Doehle, Brian P., Chang, Kristina, Rustagi, Arjun, McNevin, John, McElrath, M. Juliana, Gale, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421752/
https://ncbi.nlm.nih.gov/pubmed/22593165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00423-12
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