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A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins

The HIV-1 Vif protein suppresses the inhibition of viral replication caused by the human antiretroviral factor APOBEC3G. As a result, HIV-1 mutants that do not express the Vif protein are replication incompetent in ‘nonpermissive' cells, such as primary T cells and the T-cell line CEM, that exp...

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Detalhes bibliográficos
Main Authors: Wiegand, Heather L, Doehle, Brian P, Bogerd, Hal P, Cullen, Bryan R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC423288/
https://ncbi.nlm.nih.gov/pubmed/15152192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600246
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