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A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins

The HIV-1 Vif protein suppresses the inhibition of viral replication caused by the human antiretroviral factor APOBEC3G. As a result, HIV-1 mutants that do not express the Vif protein are replication incompetent in ‘nonpermissive' cells, such as primary T cells and the T-cell line CEM, that exp...

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Pubblicato in:EMBO J
Autori principali: Wiegand, Heather L, Doehle, Brian P, Bogerd, Hal P, Cullen, Bryan R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423288/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15152192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600246
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