Yüklüyor......

Antiretroviral Efficacy and Pharmacokinetics of Oral Bis(isopropyloxycarbonyloxymethyl)9-(2-Phosphonylmethoxypropyl)adenine in Mice

To overcome the low oral bioavailability of the highly potent and selective antiretroviral agent (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA), a new lipophilic ester derivative, i.e., the bis(isopropyloxycarbonyloxymethyl)-ester [bis(POC)-PMPA], was prepared. The usefulness of bis(POC)-PMPA as an...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Naesens, Lieve, Bischofberger, Norbert, Augustijns, Patrick, Annaert, Pieter, Van den Mooter, Guy, Arimilli, Murty N., Kim, Choung U., De Clercq, Erik
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC105646/
https://ncbi.nlm.nih.gov/pubmed/9660984
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!