Lysyl Oxidase Inhibits Ras-Mediated Transformation by Preventing Activation of NF-κB

Por Jeay, Sébastien, Pianetti, Stefania, Kagan, Herbert M., Sonenshein, Gail E.
Publicado em 2003

Enhanced efficacy of IGF1R inhibition in paediatric glioblastoma by combinatorial targeting of PDGFRα/β

Por Bielen, Aleksandra, Perryman, Lara, Box, Gary M., Valenti, Melanie, de Haven Brandon, Alexis, Martins, Vanessa, Jury, Alexa, Popov, Sergey, Gowan, Sharon, Jeay, Sebastien, Raynaud, Florence I., Hofmann, Francesco, Hargrave, Darren, Eccles, Suzanne A., Jones, Chris
Publicado em 2011

Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma

Por Carita, Guillaume, Frisch-Dit-Leitz, Estelle, Dahmani, Ahmed, Raymondie, Chloé, Cassoux, Nathalie, Piperno-Neumann, Sophie, Némati, Fariba, Laurent, Cécile, De Koning, Leanne, Halilovic, Ensar, Jeay, Sebastien, Wylie, Andrew, Emery, Caroline, Roman-Roman, Sergio, Schoumacher, Marie, Decaudin, Didier
Publicado no Oncotarget (2016)

Combined ALK and MDM2 inhibition increases antitumor activity and overcomes resistance in human ALK mutant neuroblastoma cell lines and xenograft models

Por Wang, Hui Qin, Halilovic, Ensar, Li, Xiaoyan, Liang, Jinsheng, Cao, Yichen, Rakiec, Daniel P, Ruddy, David A, Jeay, Sebastien, Wuerthner, Jens U, Timple, Noelito, Kasibhatla, Shailaja, Li, Nanxin, Williams, Juliet A, Sellers, William R, Huang, Alan, Li, Fang
Publicado no eLife (2017)

Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition

Por Bielen, Aleksandra, Box, Gary, Perryman, Lara, Bjerke, Lynn, Popov, Sergey, Jamin, Yann, Jury, Alexa, Valenti, Melanie, Brandon, Alexis de Haven, Martins, Vanessa, Romanet, Vincent, Jeay, Sebastien, Raynaud, Florence I., Hofmann, Francesco, Robinson, Simon P., Eccles, Suzanne A., Jones, Chris
Publicado em 2012

Inhibition of wild-type p53-expressing AML by novel small molecule HDM2 inhibitor, CGM097

Por Weisberg, Ellen, Halilovic, Ensar, Cooke, Vesselina G., Nonami, Atsushi, Ren, Tao, Sanda, Takaomi, Simkin, Irene, Yuan, Jing, Antonakos, Brandon, Barys, Louise, Ito, Moriko, Stone, Richard, Galinsky, Ilene, Cowens, Kristen, Nelson, Erik, Sattler, Martin, Jeay, Sebastien, Wuerthner, Jens U., McDonough, Sean M., Wiesmann, Marion, Griffin, James D.
Publicado no Mol Cancer Ther (2015)

A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097

Por Jeay, Sébastien, Gaulis, Swann, Ferretti, Stéphane, Bitter, Hans, Ito, Moriko, Valat, Thérèse, Murakami, Masato, Ruetz, Stephan, Guthy, Daniel A, Rynn, Caroline, Jensen, Michael R, Wiesmann, Marion, Kallen, Joerg, Furet, Pascal, Gessier, François, Holzer, Philipp, Masuya, Keiichi, Würthner, Jens, Halilovic, Ensar, Hofmann, Francesco, Sellers, William R, Graus Porta, Diana
Publicado no eLife (2015)

Correction: A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097

Por Jeay, Sébastien, Gaulis, Swann, Ferretti, Stéphane, Bitter, Hans, Ito, Moriko, Valat, Thérèse, Murakami, Masato, Ruetz, Stephan, Guthy, Daniel A, Rynn, Caroline, Jensen, Michael R, Wiesmann, Marion, Kallen, Joerg, Furet, Pascal, Gessier, François, Holzer, Philipp, Masuya, Keiichi, Würthner, Jens, Halilovic, Ensar, Hofmann, Francesco, Sellers, William R, Graus Porta, Diana
Publicado no eLife (2016)

Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf(−/−) mouse model

Por Chapeau, Emilie A., Gembarska, Agnieszka, Durand, Eric Y., Mandon, Emeline, Estadieu, Claire, Romanet, Vincent, Wiesmann, Marion, Tiedt, Ralph, Lehar, Joseph, de Weck, Antoine, Rad, Roland, Barys, Louise, Jeay, Sebastien, Ferretti, Stephane, Kauffmann, Audrey, Sutter, Esther, Grevot, Armelle, Moulin, Pierre, Murakami, Masato, Sellers, William R., Hofmann, Francesco, Jensen, Michael Rugaard
Publicado no Proc Natl Acad Sci U S A (2017)

A comprehensive patient-derived xenograft collection representing the heterogeneity of melanoma

Por Krepler, Clemens, Sproesser, Katrin, Brafford, Patricia, Beqiri, Marilda, Garman, Bradley, Xiao, Min, Shannan, Batool, Watters, Andrea, Perego, Michela, Zhang, Gao, Vultur, Adina, Yin, Xiangfan, Liu, Qin, Anastopoulos, Ioannis N, Wubbenhorst, Bradley, Wilson, Melissa A., Xu, Wei, Karakousis, Giorgos, Feldman, Michael, Xu, Xiaowei, Amaravadi, Ravi, Gangadhar, Tara C., Elder, David E., Haydu, Lauren E., Wargo, Jennifer A., Davies, Michael A., Lu, Yiling, Mills, Gordon B., Frederick, Dennie T., Barzily-Rokni, Michal, Flaherty, Keith T., Hoon, Dave S., Guarino, Michael, Bennett, Joseph J., Ryan, Randall W., Petrelli, Nicholas J, Shields, Carol L., Terai, Mizue, Sato, Takami, Aplin, Andrew E., Roesch, Alexander, Darr, David, Angus, Steve, Kumar, Rakesh, Halilovic, Ensar, Caponigro, Giordano, Jeay, Sebastien, Wuerthner, Jens, Walter, Annette, Ocker, Matthias, Boxer, Matthew B., Schuchter, Lynn, Nathanson, Katherine L., Herlyn, Meenhard
Publicado no Cell Rep (2017)

The Public Repository of Xenografts (ProXe) enables discovery and randomized phase II-like trials in mice

Por Townsend, Elizabeth C., Murakami, Mark A., Christodoulou, Alexandra, Christie, Amanda L., Köster, Johannes, DeSouza, Tiffany A., Morgan, Elizabeth A., Kallgren, Scott P., Liu, Huiyun, Wu, Shuo-Chieh, Plana, Olivia, Montero, Joan, Stevenson, Kristen E., Rao, Prakash, Vadhi, Raga, Andreeff, Michael, Armand, Philippe, Ballen, Karen K., Barzaghi-Rinaudo, Patrizia, Cahill, Sarah, Clark, Rachael A., Cooke, Vesselina G., Davids, Matthew S., DeAngelo, Daniel J., Dorfman, David M., Eaton, Hilary, Ebert, Benjamin L., Etchin, Julia, Firestone, Brant, Fisher, David C., Freedman, Arnold S., Galinsky, Ilene A., Gao, Hui, Garcia, Jacqueline S., Garnache-Ottou, Francine, Graubert, Timothy A., Gutierrez, Alejandro, Halilovic, Ensar, Harris, Marian H., Herbert, Zachary T., Horwitz, Steven M., Inghirami, Giorgio, Intlekoffer, Andrew M., Ito, Moriko, Izraeli, Shai, Jacobsen, Eric D., Jacobson, Caron A., Jeay, Sébastien, Jeremias, Irmela, Kelliher, Michelle A., Koch, Raphael, Konopleva, Marina, Kopp, Nadja, Kornblau, Steven M., Kung, Andrew L., Kupper, Thomas S., LaBoeuf, Nicole, LaCasce, Ann S., Lees, Emma, Li, Loretta S., Look, A. Thomas, Murakami, Masato, Muschen, Markus, Neuberg, Donna, Ng, Samuel Y., Odejide, Oreofe O., Orkin, Stuart H., Paquette, Rachel R., Place, Andrew E., Roderick, Justine E., Ryan, Jeremy A., Sallan, Stephen E., Shoji, Brent, Silverman, Lewis B., Soiffer, Robert J., Steensma, David P., Stegmaier, Kimberly, Stone, Richard M., Tamburini, Jerome, Thorner, Aaron R., van Hummelen, Paul, Wadleigh, Martha, Wiesmann, Marion, Weng, Andrew P., Wuerthner, Jens U., Williams, David A., Wollison, Bruce M., Lane, Andrew A., Letai, Anthony, Bertagnolli, Monica M., Ritz, Jerome, Brown, Myles, Long, Henry, Aster, Jon C., Shipp, Margaret A., Griffin, James D., Weinstock, David M.
Publicado no Cancer Cell (2016)