Targeting BRAF in advanced melanoma: a first step towards manageable disease

Por Vultur, Adina, Villanueva, Jessie, Herlyn, Meenhard
Publicado em 2011

Resistance to BRAF inhibitors: Unraveling mechanisms and future treatment options

Por Villanueva, Jessie, Vultur, Adina, Herlyn, Meenhard
Publicado em 2011

Inhibition of Src family kinases with dasatinib blocks migration and invasion of human melanoma cells

Por Buettner, Ralf, Mesa, Tania, Vultur, Adina, Lee, Frank, Jove, Richard
Publicado em 2008

The role of Orai–STIM calcium channels in melanocytes and melanoma

Por Stanisz, Hedwig, Vultur, Adina, Herlyn, Meenhard, Roesch, Alexander, Bogeski, Ivan
Publicado no J Physiol (2016)

Stat3 Is Required for Full Neoplastic Transformation by the Simian Virus 40 Large Tumor Antigen

Por Vultur, Adina, Arulanandam, Rozanne, Turkson, James, Niu, Guilian, Jove, Richard, Raptis, Leda
Publicado em 2005

SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells

Por Vultur, Adina, Buettner, Ralf, Kowolik, Claudia, Liang, Wei, Smith, David, Boschelli, Frank, Jove, Richard
Publicado em 2008

Organometallic Pyridylnaphthalimide Complexes as Protein Kinase Inhibitors

Por Blanck, Sebastian, Cruchter, Thomas, Vultur, Adina, Riedel, Radostan, Harms, Klaus, Herlyn, Meenhard, Meggers, Eric
Publicado em 2011

Identification of a novel family of BRAF(V600E) inhibitors

Por Qin, Jie, Xie, Peng, Ventocilla, Christian, Zhou, Guoqiang, Vultur, Adina, Chen, Quan, Liu, Qin, Herlyn, Meenhard, Winkler, Jeffrey, Marmorstein, Ronen
Publicado em 2012

A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

Por Roesch, Alexander, Fukunaga-Kalabis, Mizuho, Schmidt, Elizabeth C., Zabierowski, Susan E., Brafford, Patricia A., Vultur, Adina, Basu, Devraj, Gimotty, Phyllis, Vogt, Thomas, Herlyn, Meenhard
Publicado em 2010

Rhenium Complexes with Visible-Light-Induced Anticancer Activity

Por Kastl, Anja, Dieckmann, Sandra, Wähler, Kathrin, Völker, Timo, Kastl, Lena, Merkel, Anna Lena, Vultur, Adina, Shannan, Batool, Harms, Klaus, Ocker, Matthias, Parak, Wolfgang, Herlyn, Meenhard, Meggers, Eric
Publicado em 2013

Functional Profiling of Live Melanoma Samples Using a Novel Automated Platform

Por Schayowitz, Adam, Bertenshaw, Greg, Jeffries, Emiko, Schatz, Timothy, Cotton, James, Villanueva, Jessie, Herlyn, Meenhard, Krepler, Clemens, Vultur, Adina, Xu, Wei, Yu, Gordon H., Schuchter, Lynn, Clark, Douglas P.
Publicado em 2012

MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines

Por Vultur, Adina, Villanueva, Jessie, Krepler, Clemens, Rajan, Geena, Chen, Quan, Xiao, Min, Li, Ling, Gimotty, Phyllis A., Wilson, Melissa, Hayden, James, Keeney, Frederick, Nathanson, Katherine L., Herlyn, Meenhard
Publicado em 2013

The Anti-Melanoma Activity of Dinaciclib, a Cyclin-Dependent Kinase Inhibitor, Is Dependent on p53 Signaling

Por Desai, Brijal M., Villanueva, Jessie, Nguyen, Thierry-Thien K., Lioni, Mercedes, Xiao, Min, Kong, Jun, Krepler, Clemens, Vultur, Adina, Flaherty, Keith T., Nathanson, Katherine L., Smalley, Keiran S. M., Herlyn, Meenhard
Publicado em 2013

Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization

Por Kong, Xiangqian, Qin, Jie, Li, Zeng, Vultur, Adina, Tong, Linjiang, Feng, Enguang, Rajan, Geena, Liu, Shien, Lu, Junyan, Liang, Zhongjie, Zheng, Mingyue, Zhu, Weiliang, Jiang, Hualiang, Herlyn, Meenhard, Liu, Hong, Marmorstein, Ronen, Luo, Cheng
Publicado em 2012

The novel SMAC mimetic birinapant exhibits potent activity against human melanoma cells

Por Krepler, Clemens, Chunduru, Srinivas K., Halloran, Molly B., He, Xu, Xiao, Min, Vultur, Adina, Villanueva, Jessie, Mitsuuchi, Yasuhiro, Neiman, Eric M., Benetatos, Christopher, Nathanson, Katherine L., Amaravadi, Ravi K., Pehamberger, Hubert, McKinlay, Mark, Herlyn, Meenhard
Publicado em 2013

Enhancing the evaluation of PI3K inhibitors through 3D melanoma models

Por Shannan, Batool, Chen, Quan, Watters, Andrea, Perego, Michela, Krepler, Clemens, Thombre, Rakhee, Li, Ling, Rajan, Geena, Peterson, Scott, Gimotty, Phyllis A., Wilson, Melissa, Nathanson, Katherine L., Gangadhar, Tara C., Schuchter, Lynn M., Weeraratna, Ashani T., Herlyn, Meenhard, Vultur, Adina
Publicado no Pigment Cell Melanoma Res (2016)

Overcoming intrinsic multi-drug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells

Por Roesch, Alexander, Vultur, Adina, Bogeski, Ivan, Wang, Huan, Zimmermann, Katharina M., Speicher, David, Körbel, Christina, Laschke, Matthias W., Gimotty, Phyllis A., Philipp, Stephan E., Krause, Elmar, Pätzold, Sylvie, Villanueva, Jessie, Krepler, Clemens, Fukunaga-Kalabis, Mizuho, Hoth, Markus, Bastian, Boris, Vogt, Thomas, Herlyn, Meenhard
Publicado em 2013

Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma

Por Krepler, Clemens, Xiao, Min, Samanta, Minu, Vultur, Adina, Chen, Hsin-Yi, Brafford, Patricia, Reyes-Uribe, Patricia I., Halloran, Molly, Chen, Thomas, He, Xu, Hristova, Denitsa, Liu, Qin, Samatar, Ahmed A., Davies, Michael A., Nathanson, Katherine L., Fukunaga-Kalabis, Mizuho, Herlyn, Meenhard, Villanueva, Jessie
Publicado no Oncotarget (2016)

PIM kinases as therapeutic targets against advanced melanoma

Por Shannan, Batool, Watters, Andrea, Chen, Quan, Mollin, Stefan, Dörr, Markus, Meggers, Eric, Xu, Xiaowei, Gimotty, Phyllis A., Perego, Michela, Li, Ling, Benci, Joseph, Krepler, Clemens, Brafford, Patricia, Zhang, Jie, Wei, Zhi, Zhang, Gao, Liu, Qin, Yin, Xiangfan, Nathanson, Katherine L., Herlyn, Meenhard, Vultur, Adina
Publicado no Oncotarget (2016)

Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by co-targeting MEK and IGF-1R/PI3K

Por Villanueva, Jessie, Vultur, Adina, Lee, John T., Somasundaram, Rajasekharan, Fukunaga-Kalabis, Mizuho, Cipolla, Angela K., Wubbenhorst, Bradley, Xu, Xiaowei, Gimotty, Phyllis A., Kee, Damien, Santiago-Walker, Ademi E., Letrero, Richard, D’Andrea, Kurt, Pushparajan, Anitha, Hayden, James E., Brown, Kimberly Dahlman, Laquerre, Sylvie, McArthur, Grant A., Sosman, Jeffrey A., Nathanson, Katherine L., Herlyn, Meenhard
Publicado em 2010