The Marine-Derived Oligosaccharide Sulfate (MdOS), a Novel Multiple Tyrosine Kinase Inhibitor, Combats Tumor Angiogenesis both In Vitro and In Vivo

par Ma, Jingui, Xin, Xianliang, Meng, Linghua, Tong, Linjiang, Lin, Liping, Geng, Meiyu, Ding, Jian
Publié 2008

Discovery of a New Series of Naphthamides as Potent VEGFR-2 Kinase Inhibitors

par Lv, Yongcong, Li, Mengyuan, Liu, Ting, Tong, Linjiang, Peng, Ting, Wei, Lixin, Ding, Jian, Xie, Hua, Duan, Wenhu
Publié 2014

Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors

par Hu, Xiuqin, Wang, Disha, Tong, Yi, Tong, Linjiang, Wang, Xia, Zhu, Lili, Xie, Hua, Li, Shiliang, Yang, You, Xu, Yufang
Publié dans Front Chem (2017)

Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs

par Chen, Yun, Ning, Yi, Bai, Gang, Tong, Linjiang, Zhang, Tao, Zhou, Jinpei, Zhang, Huibin, Xie, Hua, Ding, Jian, Duan, Wenhu
Publié dans ACS Med Chem Lett (2020)

AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR

par Zhou, Yuanfeng, Chen, Yi, Tong, Linjiang, Xie, Hua, Wen, Weiwei, Zhang, Jie, Xi, Yong, Shen, Yanyan, Geng, Meiyu, Wang, Yuanyuan, Jiang, Hualiang, Luo, Cheng, Lin, Liping, Ding, Jian
Publié 2012

Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR(L858R/T790M/C797S)

par Li, Qiannan, Zhang, Tao, Li, Shiliang, Tong, Linjiang, Li, Junyu, Su, Zhicheng, Feng, Fang, Sun, Deheng, Tong, Yi, Wang, Xia, Zhao, Zhenjiang, Zhu, Lili, Ding, Jian, Li, Honglin, Xie, Hua, Xu, Yufang
Publié dans ACS Med Chem Lett (2019)

AST1306, A Novel Irreversible Inhibitor of the Epidermal Growth Factor Receptor 1 and 2, Exhibits Antitumor Activity Both In Vitro and In Vivo

par Xie, Hua, Lin, Liping, Tong, Linjiang, Jiang, Yong, Zheng, Mingyue, Chen, Zhuo, Jiang, Xiaoyan, Zhang, Xiaowei, Ren, Xiaowei, Qu, Wenchao, Yang, Yang, Wan, Hua, Chen, Yi, Zuo, Jianping, Jiang, Hualiang, Geng, Meiyu, Ding, Jian
Publié 2011

Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization

par Kong, Xiangqian, Qin, Jie, Li, Zeng, Vultur, Adina, Tong, Linjiang, Feng, Enguang, Rajan, Geena, Liu, Shien, Lu, Junyan, Liang, Zhongjie, Zheng, Mingyue, Zhu, Weiliang, Jiang, Hualiang, Herlyn, Meenhard, Liu, Hong, Marmorstein, Ronen, Luo, Cheng
Publié 2012

Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance

par Zhang, Tao, Qu, Rong, Chan, Shingpan, Lai, Mengzhen, Tong, Linjiang, Feng, Fang, Chen, Hongyu, Song, Tingting, Song, Peiran, Bai, Gang, Liu, Yingqiang, Wang, Yanan, Li, Yan, Su, Yi, Shen, Yanyan, Sun, Yiming, Chen, Yi, Geng, Meiyu, Ding, Ke, Ding, Jian, Xie, Hua
Publié dans Mol Cancer (2020)