Wordt geladen...
Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs
[Image: see text] Interleukin-1 receptor associated kinase 4 (IRAK4) is a promising therapeutic target for diffuse large B-cell lymphoma driven by MYD88 L265P mutant, acting both as a kinase and a scaffolding protein for downstream signaling molecules. While previous efforts to modulate IRAK4 activi...
Bewaard in:
| Gepubliceerd in: | ACS Med Chem Lett |
|---|---|
| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical Society
2020
|
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7812674/ https://ncbi.nlm.nih.gov/pubmed/33488968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00474 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|