AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR

Angiogenesis plays an important role in neoplastic transformation and progression as well as in the metastasis process of most human cancers. Herein, we identified AL3810 as a novel and orally bioavailable small molecular inhibitor with potent inhibitory activity against multiple tyrosine kinases in...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zhou, Yuanfeng, Chen, Yi, Tong, Linjiang, Xie, Hua, Wen, Weiwei, Zhang, Jie, Xi, Yong, Shen, Yanyan, Geng, Meiyu, Wang, Yuanyuan, Jiang, Hualiang, Luo, Cheng, Lin, Liping, Ding, Jian
التنسيق: Artigo
اللغة:Inglês
منشور في: Blackwell Publishing Ltd 2012
الموضوعات:
Original Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823425/
https://ncbi.nlm.nih.gov/pubmed/22304225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2012.01541.x
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