AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR

Angiogenesis plays an important role in neoplastic transformation and progression as well as in the metastasis process of most human cancers. Herein, we identified AL3810 as a novel and orally bioavailable small molecular inhibitor with potent inhibitory activity against multiple tyrosine kinases in...

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Detalhes bibliográficos
Main Authors: Zhou, Yuanfeng, Chen, Yi, Tong, Linjiang, Xie, Hua, Wen, Weiwei, Zhang, Jie, Xi, Yong, Shen, Yanyan, Geng, Meiyu, Wang, Yuanyuan, Jiang, Hualiang, Luo, Cheng, Lin, Liping, Ding, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823425/
https://ncbi.nlm.nih.gov/pubmed/22304225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2012.01541.x
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