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Targeting BRAF in advanced melanoma: a first step towards manageable disease
Melanoma is the deadliest form of skin cancer and its incidence has been increasing. The disease manifests itself as clinically and genetically distinct subgroups, indicating the need for patient-specific diagnostic and treatment tools. The discovery of activating mutations (V600E) in the BRAF kinas...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079374/ https://ncbi.nlm.nih.gov/pubmed/21447722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0174 |
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