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A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth
Melanomas are highly heterogeneous tumors, but the biological significance of their different subpopulations is not clear. Using the H3K4 demethylase JARID1B (KDM5B/PLU-1/RBP2-H1) as a biomarker, we have characterized a small subpopulation of slow-cycling melanoma cells that cycle with doubling time...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882693/ https://ncbi.nlm.nih.gov/pubmed/20478252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.04.020 |
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