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Lysyl Oxidase Inhibits Ras-Mediated Transformation by Preventing Activation of NF-κB

Lysyl oxidase (LO), which catalyzes the oxidation of lysine residues, was previously shown to have anti-oncogenic activity on ras-transformed cells. Since oncogenic Ras mediates transformation, in part, through the activation of the transcription factor nuclear factor-κB (NF-κB), we tested here the...

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Bibliografiske detaljer
Main Authors: Jeay, Sébastien, Pianetti, Stefania, Kagan, Herbert M., Sonenshein, Gail E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC150722/
https://ncbi.nlm.nih.gov/pubmed/12640111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2251-2263.2003
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