Lysyl Oxidase Inhibits Ras-Mediated Transformation by Preventing Activation of NF-κB

Lysyl oxidase (LO), which catalyzes the oxidation of lysine residues, was previously shown to have anti-oncogenic activity on ras-transformed cells. Since oncogenic Ras mediates transformation, in part, through the activation of the transcription factor nuclear factor-κB (NF-κB), we tested here the...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Jeay, Sébastien, Pianetti, Stefania, Kagan, Herbert M., Sonenshein, Gail E.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2003
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12640111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.7.2251-2263.2003
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