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Lysyl Oxidase Inhibits Ras-Mediated Transformation by Preventing Activation of NF-κB
Lysyl oxidase (LO), which catalyzes the oxidation of lysine residues, was previously shown to have anti-oncogenic activity on ras-transformed cells. Since oncogenic Ras mediates transformation, in part, through the activation of the transcription factor nuclear factor-κB (NF-κB), we tested here the...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150722/ https://ncbi.nlm.nih.gov/pubmed/12640111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2251-2263.2003 |
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