α-Synuclein Aggregation Monitored by Thioflavin T Fluorescence Assay

por Wördehoff, Michael M., Hoyer, Wolfgang
Publicado en Bio Protoc (2018)

Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation

por Hoyer, Wolfgang, Grönwall, Caroline, Jonsson, Andreas, Ståhl, Stefan, Härd, Torleif
Publicado 2008

Inhibitor and substrate cooperate to inhibit amyloid fibril elongation of α-synuclein

por Agerschou, Emil Dandanell, Borgmann, Vera, Wördehoff, Michael M., Hoyer, Wolfgang
Publicado en Chem Sci (2020)

Molecular-level secondary structure, polymorphism, and dynamics of full-length α-synuclein fibrils studied by solid-state NMR

por Heise, Henrike, Hoyer, Wolfgang, Becker, Stefan, Andronesi, Ovidiu C., Riedel, Dietmar, Baldus, Marc
Publicado 2005

Structural Characterization of Fibrils from Recombinant Human Islet Amyloid Polypeptide by Solid-State NMR: The Central FGAILS Segment Is Part of the β-Sheet Core

por Weirich, Franziska, Gremer, Lothar, Mirecka, Ewa A., Schiefer, Stephanie, Hoyer, Wolfgang, Heise, Henrike
Publicado en PLoS One (2016)

Recombinant amyloid beta-peptide production by coexpression with an affibody ligand

por Macao, Bertil, Hoyer, Wolfgang, Sandberg, Anders, Brorsson, Ann-Christin, Dobson, Christopher M, Härd, Torleif
Publicado 2008

Mechanism of Fibril and Soluble Oligomer Formation in Amyloid Beta and Hen Egg White Lysozyme Proteins

por Perez, Carlos, Miti, Tatiana, Hasecke, Filip, Meisl, Georg, Hoyer, Wolfgang, Muschol, Martin, Ullah, Ghanim
Publicado en J Phys Chem B (2019)

Protofibril–Fibril Interactions Inhibit Amyloid Fibril Assembly by Obstructing Secondary Nucleation

por Hasecke, Filip, Niyangoda, Chamani, Borjas, Gustavo, Pan, Jianjun, Matthews, Garrett, Muschol, Martin, Hoyer, Wolfgang
Publicado en Angew Chem Int Ed Engl (2020)

Clustering of human prion protein and α-synuclein oligomers requires the prion protein N-terminus

por Rösener, Nadine S., Gremer, Lothar, Wördehoff, Michael M., Kupreichyk, Tatsiana, Etzkorn, Manuel, Neudecker, Philipp, Hoyer, Wolfgang
Publicado en Commun Biol (2020)

β-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor

por Mirecka, Ewa A., Feuerstein, Sophie, Gremer, Lothar, Schröder, Gunnar F., Stoldt, Matthias, Willbold, Dieter, Hoyer, Wolfgang
Publicado en Sci Rep (2016)

Elucidating the multi-targeted anti-amyloid activity and enhanced islet amyloid polypeptide binding of β-wrapins

por Orr, Asuka A., Shaykhalishahi, Hamed, Mirecka, Ewa A., Jonnalagadda, Sai Vamshi R., Hoyer, Wolfgang, Tamamis, Phanourios
Publicado en Comput Chem Eng (2018)

NMR of α-synuclein–polyamine complexes elucidates the mechanism and kinetics of induced aggregation

por Fernández, Claudio O, Hoyer, Wolfgang, Zweckstetter, Markus, Jares-Erijman, Elizabeth A, Subramaniam, Vinod, Griesinger, Christian, Jovin, Thomas M
Publicado 2004

Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein

por Bertoncini, Carlos W., Jung, Young-Sang, Fernandez, Claudio O., Hoyer, Wolfgang, Griesinger, Christian, Jovin, Thomas M., Zweckstetter, Markus
Publicado 2005

Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth

por Wördehoff, Michael M., Shaykhalishahi, Hamed, Groß, Luca, Gremer, Lothar, Stoldt, Matthias, Buell, Alexander K., Willbold, Dieter, Hoyer, Wolfgang
Publicado en J Mol Biol (2017)

A d-enantiomeric peptide interferes with heteroassociation of amyloid-β oligomers and prion protein

por Rösener, Nadine S., Gremer, Lothar, Reinartz, Elke, König, Anna, Brener, Oleksandr, Heise, Henrike, Hoyer, Wolfgang, Neudecker, Philipp, Willbold, Dieter
Publicado en J Biol Chem (2018)

Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting

por Schützmann, Marie P., Hasecke, Filip, Bachmann, Sarah, Zielinski, Mara, Hänsch, Sebastian, Schröder, Gunnar F., Zempel, Hans, Hoyer, Wolfgang
Publicado en Nat Commun (2021)

Alternative Conformations of the Tau Repeat Domain in Complex with an Engineered Binding Protein

por Grüning, Clara S. R., Mirecka, Ewa A., Klein, Antonia N., Mandelkow, Eckhard, Willbold, Dieter, Marino, Stephen F., Stoldt, Matthias, Hoyer, Wolfgang
Publicado 2014

DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States

por Uluca, Boran, Viennet, Thibault, Petrović, Dušan, Shaykhalishahi, Hamed, Weirich, Franziska, Gönülalan, Ayşenur, Strodel, Birgit, Etzkorn, Manuel, Hoyer, Wolfgang, Heise, Henrike
Publicado en Biophys J (2018)

Structural details of amyloid β oligomers in complex with human prion protein as revealed by solid-state MAS NMR spectroscopy

por König, Anna S., Rösener, Nadine S., Gremer, Lothar, Tusche, Markus, Flender, Daniel, Reinartz, Elke, Hoyer, Wolfgang, Neudecker, Philipp, Willbold, Dieter, Heise, Henrike
Publicado en J Biol Chem (2021)

The Off-rate of Monomers Dissociating from Amyloid-β Protofibrils

por Grüning, Clara S. R., Klinker, Stefan, Wolff, Martin, Schneider, Mario, Toksöz, Küpra, Klein, Antonia N., Nagel-Steger, Luitgard, Willbold, Dieter, Hoyer, Wolfgang
Publicado 2013