The Off-rate of Monomers Dissociating from Amyloid-β Protofibrils

The interconversion of monomers, oligomers, and amyloid fibrils of the amyloid-β peptide (Aβ) has been implicated in the pathogenesis of Alzheimer disease. The determination of the kinetics of the individual association and dissociation reactions is hampered by the fact that forward and reverse reac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Grüning, Clara S. R., Klinker, Stefan, Wolff, Martin, Schneider, Mario, Toksöz, Küpra, Klein, Antonia N., Nagel-Steger, Luitgard, Willbold, Dieter, Hoyer, Wolfgang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2013
Pynciau:
Protein Structure and Folding
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873566/
https://ncbi.nlm.nih.gov/pubmed/24247242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.513432
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