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The Off-rate of Monomers Dissociating from Amyloid-β Protofibrils

The interconversion of monomers, oligomers, and amyloid fibrils of the amyloid-β peptide (Aβ) has been implicated in the pathogenesis of Alzheimer disease. The determination of the kinetics of the individual association and dissociation reactions is hampered by the fact that forward and reverse reac...

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書誌詳細
主要な著者: Grüning, Clara S. R., Klinker, Stefan, Wolff, Martin, Schneider, Mario, Toksöz, Küpra, Klein, Antonia N., Nagel-Steger, Luitgard, Willbold, Dieter, Hoyer, Wolfgang
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873566/
https://ncbi.nlm.nih.gov/pubmed/24247242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.513432
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