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Solution‐Based Determination of Dissociation Constants for the Binding of Aβ42 to Antibodies

Amyloid β‐peptides (Aβ) play a major role in the pathogenesis of Alzheimer's disease. Therefore, numerous monoclonal antibodies against Aβ have been developed for basic and clinical research. The present study applied fluorescence based analytical ultracentrifugation and microscale thermophores...

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Detalhes bibliográficos
Publicado no:ChemistryOpen
Main Authors: Zhang, Tao, Nagel‐Steger, Luitgard, Willbold, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643301/
https://ncbi.nlm.nih.gov/pubmed/31367507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201900167
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