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Solution‐Based Determination of Dissociation Constants for the Binding of Aβ42 to Antibodies

Amyloid β‐peptides (Aβ) play a major role in the pathogenesis of Alzheimer's disease. Therefore, numerous monoclonal antibodies against Aβ have been developed for basic and clinical research. The present study applied fluorescence based analytical ultracentrifugation and microscale thermophores...

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Bibliografiske detaljer
Udgivet i:ChemistryOpen
Main Authors: Zhang, Tao, Nagel‐Steger, Luitgard, Willbold, Dieter
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643301/
https://ncbi.nlm.nih.gov/pubmed/31367507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201900167
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