Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution

Amyloid β (Aβ) oligomers may play a decisive role in Alzheimer’s disease related neurodegeneration, but their structural properties are poorly understood. In this report, sedimentation velocity centrifugation, small angle neutron scattering (SANS) and molecular modelling were used to identify the sm...

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Foilsithe in:Sci Rep
Main Authors: Wolff, Martin, Zhang-Haagen, Bo, Decker, Christina, Barz, Bogdan, Schneider, Mario, Biehl, Ralf, Radulescu, Aurel, Strodel, Birgit, Willbold, Dieter, Nagel-Steger, Luitgard
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449387/
https://ncbi.nlm.nih.gov/pubmed/28559586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02370-3
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