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Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution

Amyloid β (Aβ) oligomers may play a decisive role in Alzheimer’s disease related neurodegeneration, but their structural properties are poorly understood. In this report, sedimentation velocity centrifugation, small angle neutron scattering (SANS) and molecular modelling were used to identify the sm...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Wolff, Martin, Zhang-Haagen, Bo, Decker, Christina, Barz, Bogdan, Schneider, Mario, Biehl, Ralf, Radulescu, Aurel, Strodel, Birgit, Willbold, Dieter, Nagel-Steger, Luitgard
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449387/
https://ncbi.nlm.nih.gov/pubmed/28559586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02370-3
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