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Recombinant amyloid beta-peptide production by coexpression with an affibody ligand

BACKGROUND: Oligomeric and fibrillar aggregates of the amyloid β-peptide (Aβ) have been implicated in the pathogenesis of Alzheimer's disease (AD). The characterization of Aβ assemblies is essential for the elucidation of the mechanisms of Aβ neurotoxicity, but requires large quantities of pure...

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Detalhes bibliográficos
Main Authors: Macao, Bertil, Hoyer, Wolfgang, Sandberg, Anders, Brorsson, Ann-Christin, Dobson, Christopher M, Härd, Torleif
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606684/
https://ncbi.nlm.nih.gov/pubmed/18973685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-8-82
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