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Amyloid-β Protofibrils: Size, Morphology and Synaptotoxicity of an Engineered Mimic
Structural and biochemical studies of the aggregation of the amyloid-β peptide (Aβ) are important to understand the mechanisms of Alzheimer's disease, but research is complicated by aggregate inhomogeneity and instability. We previously engineered a hairpin form of Aβ called Aβcc, which forms s...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3699592/ https://ncbi.nlm.nih.gov/pubmed/23843949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066101 |
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