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Identification of proteins that specifically recognize and bind protofibrillar aggregates of amyloid-β

Protofibrils of the 42 amino acids long amyloid-β peptide are transient pre-fibrillar intermediates in the process of peptide aggregation into amyloid plaques and are thought to play a critical role in the pathology of Alzheimer’s disease. Hence, there is a need for research reagents and potential d...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Wahlberg, Elisabet, Rahman, M. Mahafuzur, Lindberg, Hanna, Gunneriusson, Elin, Schmuck, Benjamin, Lendel, Christofer, Sandgren, Mats, Löfblom, John, Ståhl, Stefan, Härd, Torleif
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519597/
https://ncbi.nlm.nih.gov/pubmed/28729665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06377-8
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