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Structural basis for high-affinity HER2 receptor binding by an engineered protein
The human epidermal growth factor receptor 2 (HER2) is specifically overexpressed in tumors of several cancers, including an aggressive form of breast cancer. It is therefore a target for both cancer diagnostics and therapy. The 58 amino acid residue Zher2 affibody molecule was previously engineered...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930565/ https://ncbi.nlm.nih.gov/pubmed/20696930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005025107 |
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