Sequestration of the Aβ Peptide Prevents Toxicity and Promotes Degradation In Vivo

Protein aggregation, arising from the failure of the cell to regulate the synthesis or degradation of aggregation-prone proteins, underlies many neurodegenerative disorders. However, the balance between the synthesis, clearance, and assembly of misfolded proteins into neurotoxic aggregates remains p...

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Detalhes bibliográficos
Main Authors: Luheshi, Leila M., Hoyer, Wolfgang, de Barros, Teresa Pereira, van Dijk Härd, Iris, Brorsson, Ann-Christin, Macao, Bertil, Persson, Cecilia, Crowther, Damian C., Lomas, David A., Ståhl, Stefan, Dobson, Christopher M., Härd, Torleif
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838747/
https://ncbi.nlm.nih.gov/pubmed/20305716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000334
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