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Mechanism of Fibril and Soluble Oligomer Formation in Amyloid Beta and Hen Egg White Lysozyme Proteins

Assembly and deposition of insoluble amyloid fibrils with a distinctive cross-β sheet structure is the molecular hallmark of amyloidogenic diseases affecting the central nervous system as well as non-neuropathic amyloidosis. Amyloidogenic proteins form aggregates via kinetic pathways dictated by ini...

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Bibliografiska uppgifter
I publikationen:J Phys Chem B
Huvudupphovsmän: Perez, Carlos, Miti, Tatiana, Hasecke, Filip, Meisl, Georg, Hoyer, Wolfgang, Muschol, Martin, Ullah, Ghanim
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839771/
https://ncbi.nlm.nih.gov/pubmed/31246474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b02338
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