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Origin of metastable oligomers and their effects on amyloid fibril self-assembly
Assembly of rigid amyloid fibrils with their characteristic cross-β sheet structure is a molecular signature of numerous neurodegenerative and non-neuropathic disorders. Frequently large populations of small globular amyloid oligomers (gOs) and curvilinear fibrils (CFs) precede the formation of late...
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| Veröffentlicht in: | Chem Sci |
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| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Royal Society of Chemistry
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6050532/ https://ncbi.nlm.nih.gov/pubmed/30079208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01479e |
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