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A d-enantiomeric peptide interferes with heteroassociation of amyloid-β oligomers and prion protein
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of people worldwide. One AD hallmark is the aggregation of β-amyloid (Aβ) into soluble oligomers and insoluble fibrils. Several studies have reported that oligomers rather than fibrils are the most toxic...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6187637/ https://ncbi.nlm.nih.gov/pubmed/30131337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003116 |
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