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The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

While amyloid-β protein (Aβ) aggregation into insoluble plaques is one of the pathological hallmarks of Alzheimer’s disease (AD), soluble oligomeric Aβ has been hypothesized to be responsible for synapse damage, neurodegeneration, learning, and memory deficits in AD. Here, we investigate the in vitr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: van Groen, Thomas, Schemmert, Sarah, Brener, Oleksandr, Gremer, Lothar, Ziehm, Tamar, Tusche, Markus, Nagel-Steger, Luitgard, Kadish, Inga, Schartmann, Elena, Elfgen, Anne, Jürgens, Dagmar, Willuweit, Antje, Kutzsche, Janine, Willbold, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701182/
https://ncbi.nlm.nih.gov/pubmed/29176708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16565-1
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