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Optimization of the All-D Peptide D3 for Aβ Oligomer Elimination

The aggregation of amyloid-β (Aβ) is postulated to be the crucial event in Alzheimer’s disease (AD). In particular, small neurotoxic Aβ oligomers are considered to be responsible for the development and progression of AD. Therefore, elimination of thesis oligomers represents a potential causal thera...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Klein, Antonia Nicole, Ziehm, Tamar, Tusche, Markus, Buitenhuis, Johan, Bartnik, Dirk, Boeddrich, Annett, Wiglenda, Thomas, Wanker, Erich, Funke, Susanne Aileen, Brener, Oleksandr, Gremer, Lothar, Kutzsche, Janine, Willbold, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841555/
https://ncbi.nlm.nih.gov/pubmed/27105346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153035
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