QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers

Strong evidence exists for a central role of amyloid β-protein (Aβ) oligomers in the pathogenesis of Alzheimer’s disease. We have developed a fast, reliable and robust in vitro assay, termed QIAD, to quantify the effect of any compound on the Aβ aggregate size distribution. Applying QIAD, we studied...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Brener, Oleksandr, Dunkelmann, Tina, Gremer, Lothar, van Groen, Thomas, Mirecka, Ewa A., Kadish, Inga, Willuweit, Antje, Kutzsche, Janine, Jürgens, Dagmar, Rudolph, Stephan, Tusche, Markus, Bongen, Patrick, Pietruszka, Jörg, Oesterhelt, Filipp, Langen, Karl-Josef, Demuth, Hans-Ulrich, Janssen, Arnold, Hoyer, Wolfgang, Funke, Susanne A., Nagel-Steger, Luitgard, Willbold, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585794/
https://ncbi.nlm.nih.gov/pubmed/26394756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13222
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados