Immobilization of Homogeneous Monomeric, Oligomeric and Fibrillar Aβ Species for Reliable SPR Measurements

There is strong evidence that the amyloid-beta peptide (Aβ) plays a central role in the pathogenesis of Alzheimer's disease (AD). In this context, a detailed quantitative description of the interactions with different Aβ species is essential for characterization of physiological and artificial...

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Main Authors: Frenzel, Daniel, Glück, Julian M., Brener, Oleksandr, Oesterhelt, Filipp, Nagel-Steger, Luitgard, Willbold, Dieter
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940443/
https://ncbi.nlm.nih.gov/pubmed/24594736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089490
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