Fibril structure of amyloid-ß(1-42) by cryo-electron microscopy

Amyloids are implicated in neurodegenerative diseases. Fibrillar aggregates of the amyloid-β protein (Aβ) are the main component of the senile plaques found in brains of Alzheimer’s disease patients. We present the structure of an Aβ(1-42) fibril composed of two intertwined protofilaments determined...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Gremer, Lothar, Schölzel, Daniel, Schenk, Carla, Reinartz, Elke, Labahn, Jörg, Ravelli, Raimond B.G., Tusche, Markus, Lopez-Iglesias, Carmen, Hoyer, Wolfgang, Heise, Henrike, Willbold, Dieter, Schröder, Gunnar F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080689/
https://ncbi.nlm.nih.gov/pubmed/28882996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao2825
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