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Fibril structure of amyloid-ß(1-42) by cryo-electron microscopy
Amyloids are implicated in neurodegenerative diseases. Fibrillar aggregates of the amyloid-β protein (Aβ) are the main component of the senile plaques found in brains of Alzheimer’s disease patients. We present the structure of an Aβ(1-42) fibril composed of two intertwined protofilaments determined...
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| Publicado en: | Science |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6080689/ https://ncbi.nlm.nih.gov/pubmed/28882996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao2825 |
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