Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy

High resolution structural information on amyloid fibrils is crucial for the understanding of their formation mechanisms and for the rational design of amyloid inhibitors in the context of protein misfolding diseases. The Src-homology 3 domain of phosphatidyl-inositol-3-kinase (PI3K-SH3) is a model...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Röder, Christine, Vettore, Nicola, Mangels, Lena N., Gremer, Lothar, Ravelli, Raimond B. G., Willbold, Dieter, Hoyer, Wolfgang, Buell, Alexander K., Schröder, Gunnar F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704188/
https://ncbi.nlm.nih.gov/pubmed/31434882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11320-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados