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Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth
Parkinson's disease is the second most common neurodegenerative disease. It is characterized by aggregation of the protein α-synuclein (α-syn) in Lewy bodies, mitochondrial dysfunction, and increased oxidative stress in the substantia nigra. Oxidative stress leads to several modifications of bi...
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| Vydáno v: | J Mol Biol |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5637163/ https://ncbi.nlm.nih.gov/pubmed/28918091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.09.005 |
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