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A near atomic-scale view at the composition of amyloid-beta fibrils by atom probe tomography

Amyloid-beta (Ab) proteins play an important role in a number of neurodegenerative diseases. Ab is found in senile plaques in brains of Alzeimer’s disease patients. The 42 residues of the monomer form dimers which stack to fibrils gaining several micrometers in length. Using Ab fibrils with (13)C an...

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書目詳細資料
發表在:Sci Rep
Main Authors: Rusitzka, Kristiane A. K., Stephenson, Leigh T., Szczepaniak, Agnieszka, Gremer, Lothar, Raabe, Dierk, Willbold, Dieter, Gault, Baptiste
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279744/
https://ncbi.nlm.nih.gov/pubmed/30514971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36110-y
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