A d-enantiomeric peptide interferes with heteroassociation of amyloid-β oligomers and prion protein

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of people worldwide. One AD hallmark is the aggregation of β-amyloid (Aβ) into soluble oligomers and insoluble fibrils. Several studies have reported that oligomers rather than fibrils are the most toxic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Rösener, Nadine S., Gremer, Lothar, Reinartz, Elke, König, Anna, Brener, Oleksandr, Heise, Henrike, Hoyer, Wolfgang, Neudecker, Philipp, Willbold, Dieter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187637/
https://ncbi.nlm.nih.gov/pubmed/30131337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003116
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