α-Synuclein Aggregation Monitored by Thioflavin T Fluorescence Assay

by Wördehoff, Michael M., Hoyer, Wolfgang
Published in Bio Protoc (2018)

Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation

by Hoyer, Wolfgang, Grönwall, Caroline, Jonsson, Andreas, Ståhl, Stefan, Härd, Torleif
Published 2008

Inhibitor and substrate cooperate to inhibit amyloid fibril elongation of α-synuclein

by Agerschou, Emil Dandanell, Borgmann, Vera, Wördehoff, Michael M., Hoyer, Wolfgang
Published in Chem Sci (2020)

Molecular-level secondary structure, polymorphism, and dynamics of full-length α-synuclein fibrils studied by solid-state NMR

by Heise, Henrike, Hoyer, Wolfgang, Becker, Stefan, Andronesi, Ovidiu C., Riedel, Dietmar, Baldus, Marc
Published 2005

Structural Characterization of Fibrils from Recombinant Human Islet Amyloid Polypeptide by Solid-State NMR: The Central FGAILS Segment Is Part of the β-Sheet Core

by Weirich, Franziska, Gremer, Lothar, Mirecka, Ewa A., Schiefer, Stephanie, Hoyer, Wolfgang, Heise, Henrike
Published in PLoS One (2016)

Recombinant amyloid beta-peptide production by coexpression with an affibody ligand

by Macao, Bertil, Hoyer, Wolfgang, Sandberg, Anders, Brorsson, Ann-Christin, Dobson, Christopher M, Härd, Torleif
Published 2008

Mechanism of Fibril and Soluble Oligomer Formation in Amyloid Beta and Hen Egg White Lysozyme Proteins

by Perez, Carlos, Miti, Tatiana, Hasecke, Filip, Meisl, Georg, Hoyer, Wolfgang, Muschol, Martin, Ullah, Ghanim
Published in J Phys Chem B (2019)

Protofibril–Fibril Interactions Inhibit Amyloid Fibril Assembly by Obstructing Secondary Nucleation

by Hasecke, Filip, Niyangoda, Chamani, Borjas, Gustavo, Pan, Jianjun, Matthews, Garrett, Muschol, Martin, Hoyer, Wolfgang
Published in Angew Chem Int Ed Engl (2020)

Clustering of human prion protein and α-synuclein oligomers requires the prion protein N-terminus

by Rösener, Nadine S., Gremer, Lothar, Wördehoff, Michael M., Kupreichyk, Tatsiana, Etzkorn, Manuel, Neudecker, Philipp, Hoyer, Wolfgang
Published in Commun Biol (2020)

β-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor

by Mirecka, Ewa A., Feuerstein, Sophie, Gremer, Lothar, Schröder, Gunnar F., Stoldt, Matthias, Willbold, Dieter, Hoyer, Wolfgang
Published in Sci Rep (2016)

Elucidating the multi-targeted anti-amyloid activity and enhanced islet amyloid polypeptide binding of β-wrapins

by Orr, Asuka A., Shaykhalishahi, Hamed, Mirecka, Ewa A., Jonnalagadda, Sai Vamshi R., Hoyer, Wolfgang, Tamamis, Phanourios
Published in Comput Chem Eng (2018)

NMR of α-synuclein–polyamine complexes elucidates the mechanism and kinetics of induced aggregation

by Fernández, Claudio O, Hoyer, Wolfgang, Zweckstetter, Markus, Jares-Erijman, Elizabeth A, Subramaniam, Vinod, Griesinger, Christian, Jovin, Thomas M
Published 2004

Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein

by Bertoncini, Carlos W., Jung, Young-Sang, Fernandez, Claudio O., Hoyer, Wolfgang, Griesinger, Christian, Jovin, Thomas M., Zweckstetter, Markus
Published 2005

Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth

by Wördehoff, Michael M., Shaykhalishahi, Hamed, Groß, Luca, Gremer, Lothar, Stoldt, Matthias, Buell, Alexander K., Willbold, Dieter, Hoyer, Wolfgang
Published in J Mol Biol (2017)

A d-enantiomeric peptide interferes with heteroassociation of amyloid-β oligomers and prion protein

by Rösener, Nadine S., Gremer, Lothar, Reinartz, Elke, König, Anna, Brener, Oleksandr, Heise, Henrike, Hoyer, Wolfgang, Neudecker, Philipp, Willbold, Dieter
Published in J Biol Chem (2018)

Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting

by Schützmann, Marie P., Hasecke, Filip, Bachmann, Sarah, Zielinski, Mara, Hänsch, Sebastian, Schröder, Gunnar F., Zempel, Hans, Hoyer, Wolfgang
Published in Nat Commun (2021)

Alternative Conformations of the Tau Repeat Domain in Complex with an Engineered Binding Protein

by Grüning, Clara S. R., Mirecka, Ewa A., Klein, Antonia N., Mandelkow, Eckhard, Willbold, Dieter, Marino, Stephen F., Stoldt, Matthias, Hoyer, Wolfgang
Published 2014

DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States

by Uluca, Boran, Viennet, Thibault, Petrović, Dušan, Shaykhalishahi, Hamed, Weirich, Franziska, Gönülalan, Ayşenur, Strodel, Birgit, Etzkorn, Manuel, Hoyer, Wolfgang, Heise, Henrike
Published in Biophys J (2018)

Structural details of amyloid β oligomers in complex with human prion protein as revealed by solid-state MAS NMR spectroscopy

by König, Anna S., Rösener, Nadine S., Gremer, Lothar, Tusche, Markus, Flender, Daniel, Reinartz, Elke, Hoyer, Wolfgang, Neudecker, Philipp, Willbold, Dieter, Heise, Henrike
Published in J Biol Chem (2021)

The Off-rate of Monomers Dissociating from Amyloid-β Protofibrils

by Grüning, Clara S. R., Klinker, Stefan, Wolff, Martin, Schneider, Mario, Toksöz, Küpra, Klein, Antonia N., Nagel-Steger, Luitgard, Willbold, Dieter, Hoyer, Wolfgang
Published 2013