Flicking the molecular switch underlying MLKL-mediated necroptosis

Bằng Hildebrand, Joanne M, Lucet, Isabelle S, Murphy, James M
Xuất bản năm Mol Cell Oncol (2015)

A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes

Bằng Lin, Wai W., Hildebrand, Joanne M., Bishop, Gail A.
Được phát hành 2013

The Role of the Key Effector of Necroptotic Cell Death, MLKL, in Mouse Models of Disease

Bằng Tovey Crutchfield, Emma C., Garnish, Sarah E., Hildebrand, Joanne M.
Xuất bản năm Biomolecules (2021)

Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions

Bằng Hildebrand, Joanne M., Yi, Zuoan, Buchta, Claire M., Poovassery, Jayakumar, Stunz, Laura L., Bishop, Gail A.
Được phát hành 2011

Synaptic Zn(2) (+) and febrile seizure susceptibility

Bằng Reid, Christopher A, Hildebrand, Michael S, Mullen, Saul A, Hildebrand, Joanne M, Berkovic, Samuel F, Petrou, Steven
Xuất bản năm Br J Pharmacol (2016)

Nuclear TRAF3 is a negative regulator of CREB in B cells

Bằng Mambetsariev, Nurbek, Lin, Wai W., Stunz, Laura L., Hanson, Brett M., Hildebrand, Joanne M., Bishop, Gail A.
Xuất bản năm Proc Natl Acad Sci U S A (2016)

A family harboring an MLKL loss of function variant implicates impaired necroptosis in diabetes

Bằng Hildebrand, Joanne M., Lo, Bernice, Tomei, Sara, Mattei, Valentina, Young, Samuel N., Fitzgibbon, Cheree, Murphy, James M., Fadda, Abeer
Xuất bản năm Cell Death Dis (2021)

The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis

Bằng Moujalled, Diane, Gangatirkar, Pradnya, Kauppi, Maria, Corbin, Jason, Lebois, Marion, Murphy, James M., Lalaoui, Najoua, Hildebrand, Joanne M., Silke, John, Alexander, Warren S., Josefsson, Emma C.
Xuất bản năm Cell Death Dis (2021)

Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted

Bằng Stutz, Michael D., Ojaimi, Samar, Allison, Cody, Preston, Simon, Arandjelovic, Philip, Hildebrand, Joanne M., Sandow, Jarrod J., Webb, Andrew I., Silke, John, Alexander, Warren S., Pellegrini, Marc
Xuất bản năm Cell Death Differ (2017)

A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs

Bằng Murai, Shin, Yamaguchi, Yoshifumi, Shirasaki, Yoshitaka, Yamagishi, Mai, Shindo, Ryodai, Hildebrand, Joanne M., Miura, Ryosuke, Nakabayashi, Osamu, Totsuka, Mamoru, Tomida, Taichiro, Adachi-Akahane, Satomi, Uemura, Sotaro, Silke, John, Yagita, Hideo, Miura, Masayuki, Nakano, Hiroyasu
Xuất bản năm Nat Commun (2018)

Addendum: A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs

Bằng Murai, Shin, Yamaguchi, Yoshifumi, Shirasaki, Yoshitaka, Yamagishi, Mai, Shindo, Ryodai, Hildebrand, Joanne M., Miura, Ryosuke, Nakabayashi, Osamu, Totsuka, Mamoru, Tomida, Taichiro, Adachi-Akahane, Satomi, Uemura, Sotaro, Silke, John, Yagita, Hideo, Miura, Masayuki, Nakano, Hiroyasu
Xuất bản năm Nat Commun (2019)

A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling

Bằng Hildebrand, Joanne M., Luo, Zhenghua, Manske, Michelle K., Price-Troska, Tammy, Ziesmer, Steven C., Lin, Wai, Hostager, Bruce S., Slager, Susan L., Witzig, Thomas E., Ansell, Stephen M., Cerhan, James R., Bishop, Gail A., Novak, Anne J.
Được phát hành 2010

A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells

Bằng Samson, André L., Fitzgibbon, Cheree, Patel, Komal M., Hildebrand, Joanne M., Whitehead, Lachlan W., Rimes, Joel S., Jacobsen, Annette V., Horne, Christopher R., Gavin, Xavier J., Young, Samuel N., Rogers, Kelly L., Hawkins, Edwin D., Murphy, James M.
Xuất bản năm Cell Death Differ (2021)

Is SIRT2 required for necroptosis?

Bằng Newton, Kim, Hildebrand, Joanne M., Shen, Zhirong, Rodriguez, Diego, Alvarez-Diaz, Silvia, Petersen, Sean, Shah, Saumil, Dugger, Debra L., Huang, Chunzi, Auwerx, Johan, Vandenabeele, Peter, Green, Douglas R., Ashkenazi, Avi, Dixit, Vishva M., Kaiser, William J., Strasser, Andreas, Degterev, Alexei, Silke, John
Được phát hành 2014

Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways

Bằng Tanzer, Maria C, Khan, Nufail, Rickard, James A, Etemadi, Nima, Lalaoui, Najoua, Spall, Sukhdeep Kaur, Hildebrand, Joanne M, Segal, David, Miasari, Maria, Chau, Diep, Wong, WendyWei-Lynn, McKinlay, Mark, Chunduru, Srinivas K, Benetatos, Christopher A, Condon, Stephen M, Vince, James E, Herold, Marco J, Silke, John
Xuất bản năm Cell Death Differ (2017)

Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies

Bằng Petrie, Emma J., Birkinshaw, Richard W., Koide, Akiko, Denbaum, Eric, Hildebrand, Joanne M., Garnish, Sarah E., Davies, Katherine A., Sandow, Jarrod J., Samson, Andre L., Gavin, Xavier, Fitzgibbon, Cheree, Young, Samuel N., Hennessy, Patrick J., Smith, Phoebe P. C., Webb, Andrew I., Czabotar, Peter E., Koide, Shohei, Murphy, James M.
Xuất bản năm Proc Natl Acad Sci U S A (2020)

Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis

Bằng Garnish, Sarah E., Meng, Yanxiang, Koide, Akiko, Sandow, Jarrod J., Denbaum, Eric, Jacobsen, Annette V., Yeung, Wayland, Samson, Andre L., Horne, Christopher R., Fitzgibbon, Cheree, Young, Samuel N., Smith, Phoebe P. C., Webb, Andrew I., Petrie, Emma J., Hildebrand, Joanne M., Kannan, Natarajan, Czabotar, Peter E., Koide, Shohei, Murphy, James M.
Xuất bản năm Nat Commun (2021)

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Bằng Hildebrand, Joanne M., Tanzer, Maria C., Lucet, Isabelle S., Young, Samuel N., Spall, Sukhdeep K., Sharma, Pooja, Pierotti, Catia, Garnier, Jean-Marc, Dobson, Renwick C. J., Webb, Andrew I., Tripaydonis, Anne, Babon, Jeffrey J., Mulcair, Mark D., Scanlon, Martin J., Alexander, Warren S., Wilks, Andrew F., Czabotar, Peter E., Lessene, Guillaume, Murphy, James M., Silke, John
Được phát hành 2014

Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis

Bằng Petrie, Emma J., Sandow, Jarrod J., Jacobsen, Annette V., Smith, Brian J., Griffin, Michael D. W., Lucet, Isabelle S., Dai, Weiwen, Young, Samuel N., Tanzer, Maria C., Wardak, Ahmad, Liang, Lung-Yu, Cowan, Angus D., Hildebrand, Joanne M., Kersten, Wilhelmus J. A., Lessene, Guillaume, Silke, John, Czabotar, Peter E., Webb, Andrew I., Murphy, James M.
Xuất bản năm Nat Commun (2018)

EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

Bằng Pearson, Jaclyn S., Giogha, Cristina, Mühlen, Sabrina, Nachbur, Ueli, Pham, Chi L. L., Zhang, Ying, Hildebrand, Joanne M., Oates, Clare V., Lung, Tania Wong Fok, Ingle, Danielle, Dagley, Laura F., Bankovacki, Aleksandra, Petrie, Emma J., Schroeder, Gunnar N., Crepin, Valerie F., Frankel, Gad, Masters, Seth L., Vince, James, Murphy, James M., Sunde, Margaret, Webb, Andrew I., Silke, John, Hartland, Elizabeth L.
Xuất bản năm Nat Microbiol (2017)