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The Role of the Key Effector of Necroptotic Cell Death, MLKL, in Mouse Models of Disease

Necroptosis is an inflammatory form of lytic programmed cell death that is thought to have evolved to defend against pathogens. Genetic deletion of the terminal effector protein—MLKL—shows no overt phenotype in the C57BL/6 mouse strain under conventional laboratory housing conditions. Small molecule...

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Detaylı Bibliyografya
Yayımlandı:Biomolecules
Asıl Yazarlar: Tovey Crutchfield, Emma C., Garnish, Sarah E., Hildebrand, Joanne M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227991/
https://ncbi.nlm.nih.gov/pubmed/34071602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060803
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