The Role of the Key Effector of Necroptotic Cell Death, MLKL, in Mouse Models of Disease

Necroptosis is an inflammatory form of lytic programmed cell death that is thought to have evolved to defend against pathogens. Genetic deletion of the terminal effector protein—MLKL—shows no overt phenotype in the C57BL/6 mouse strain under conventional laboratory housing conditions. Small molecule...

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Bibliografiska uppgifter
I publikationen:Biomolecules
Huvudupphovsmän: Tovey Crutchfield, Emma C., Garnish, Sarah E., Hildebrand, Joanne M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227991/
https://ncbi.nlm.nih.gov/pubmed/34071602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060803
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